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EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function
Authors: Sonali Bahl, Hongbo Ling, Nuwan P N Acharige, Irene Santos-Barriopedro, Mary Kay H Pflum, Edward Seto
Journal: Cell Death Dis
PubMed ID: 33976119
Doi: 10.1038/s41419-021-03697-6
Products & Services: Mutant Libraries   
Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering
Authors: Nicolas O Jørgensen, Rasmus Kjøbsted, Magnus R Larsen, Jesper B Birk, Nicoline R Andersen, Bina Albuquerque, Peter Schjerling, Russell Miller, David Carling, Christian K Pehmøller, Jørgen F P Wojtaszewski
Journal: Mol Metab
PubMed ID: 34033941
Doi: 10.1016/j.molmet.2021.101259
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YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways
Authors: Wen-Bin Ou, Meijun Z Lundberg, Shuihao Zhu, Nacef Bahri, Anastasios Kyriazoglou, Liangliang Xu, Ting Chen, Adrian Mariño-Enriquez, Jonathan A Fletcher
Journal: Oncogenesis
PubMed ID: 33947829
Doi: 10.1038/s41389-021-00327-w
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The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation
Authors: Emanuela Senatore, Francesco Chiuso, Laura Rinaldi, Daniela Intartaglia, Rossella Delle Donne, Emilia Pedone, Bruno Catalanotti, Luciano Pirone, Bianca Fiorillo, Federica Moraca, Giuliana Giamundo, Giovanni Scala, Andrea Raffeiner, Omar Torres-Quesada, Eduard Stefan, Marcel Kwiatkowski, Alienke van Pijkeren, Manuela Morleo, Brunella Franco, Corrado Garbi, Ivan Conte, Antonio Feliciello
Journal: EMBO J
PubMed ID: 33934390
Doi: 10.15252/embj.2020106503
Products & Services: Mutant Libraries   
A nematode-derived, mitochondrial stress signaling-regulated peptide exhibits broad antibacterial activity
Authors: Madhab Sapkota, Mohammed Adnan Qureshi, Siraje Arif Mahmud, Yves Balikosa, Charlton Nguyen, Joseph M Boll, Mark W Pellegrino
Journal: Biol Open
PubMed ID: 34184732
Doi: 10.1242/bio.058613
Products & Services: Peptide Synthesis   
The aminosterol Claramine inhibits β-secretase 1-mediated insulin receptor cleavage
Authors: Bénédicte Gaborit, Roland Govers, Alexandre Altié, Jean Michel Brunel, Pierre Morange, Franck Peiretti
Journal: J Biol Chem
PubMed ID: 34029592
Doi: 10.1016/j.jbc.2021.100818
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Binding Models of Copper(II) Thiosemicarbazone Complexes with Human Serum Albumin: A Speciation Study
Authors: Nóra V May, Attila Jancsó, Éva A Enyedy
Journal: Molecules
PubMed ID: 34063080
Doi: 10.3390/molecules26092711
Products & Services: Stable Cell Lines   
Bifidobacterium response to lactulose ingestion in the gut relies on a solute-binding protein-dependent ABC transporter
Authors: Keisuke Yoshida, Rika Hirano, Yohei Sakai, Moonhak Choi, Mikiyasu Sakanaka, Shin Kurihara, Hisakazu Iino, Jin-Zhong Xiao, Takane Katayama, Toshitaka Odamaki
Journal: Commun Biol
PubMed ID: 33972677
Doi: 10.1038/s42003-021-02072-7
Products & Services: Gene Synthesis   
Nanomolar Pulse Dipolar EPR Spectroscopy in Proteins: Cu-Cu and Nitroxide-Nitroxide Cases
Authors: Katrin Ackermann, Joshua L Wort, Bela E Bode
Journal: J Phys Chem B
PubMed ID: 33998795
Doi: 10.1021/acs.jpcb.1c03666
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Protein Sumoylation Is Crucial for Phagocytosis in Trophozoites
Authors: Mitzi Díaz-Hernández, Rosario Javier-Reyna, Izaid Sotto-Ortega, Guillermina García-Rivera, Sarita Montaño, Abigail Betanzos, Dxinegueela Zanatta, Esther Orozco
Journal: Int J Mol Sci
PubMed ID: 34071922
Doi: 10.3390/ijms22115709
Products & Services: Peptide Synthesis