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Splice-switch oligonucleotide-based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC-driven hepatocellular carcinoma
Authors: Dexter Kai Hao Thng, Tan Boon Toh, Paolo Pigini, Lissa Hooi, Yock Young Dan, Pierce Kah-Hoe Chow, Glenn Kunnath Bonney, Masturah Bte Mohd Abdul Rashid, Ernesto Guccione, Dave Keng Boon Wee, Edward Kai-Hua Chow
Journal: Bioeng Transl Med
PubMed ID: 36684069
Doi: 10.1002/btm2.10363
Products & Services: Proteins, Expression, Isolation and Analysis   
Body Weight is Inversely Associated with Anti-SARS-CoV-2 Antibody Levels after BNT162b2 mRNA Vaccination in Young and Middle Aged Adults
Authors: Su Youn Nam, Seong Woo Jeon, Deuk Kju Jung, Sung-Jae Heo
Journal: Infect Chemother
PubMed ID: 36196609
Doi: 10.3947/ic.2022.0089
Products & Services: Recombinant Proteins   
PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
Authors: Jeetendra Kumar Nag, Hodaya Malka, Shoshana Sedley, Priyanga Appasamy, Tatyana Rudina, Tgst Levi, Amnon Hoffman, Chaim Gilon, Beatrice Uziely, Rachel Bar-Shavit
Journal: Mol Cancer Ther
PubMed ID: 36066448
Doi: 10.1158/1535-7163.MCT-21-0946
Products & Services: Catalog Peptides   
Activated AMP-activated protein kinase prevents hepatic steatosis, oxidative stress and inflammation in primary chicken hepatocytes
Authors: Yao Yao, Longlong Li, Huihui Wang, Ying Yang, Haitian Ma
Journal: Front Physiol
PubMed ID: 36160867
Doi: 10.3389/fphys.2022.974825
Products & Services: Gene Synthesis   
A nuclear import pathway exploited by pathogenic noncoding RNAs
Authors: Junfei Ma, Shachinthaka D Dissanayaka Mudiyanselage, Woong June Park, Mo Wang, Ryuta Takeda, Bin Liu, Ying Wang
Journal: Plant Cell
PubMed ID: 35877068
Doi: 10.1093/plcell/koac210
Products & Services: Proteins, Expression, Isolation and Analysis   
The CD4 T cell response to a commensal-derived epitope transitions from a tolerant to an inflammatory state in Crohn's disease
Authors: Thomas K Pedersen, Eric M Brown, Damian R Plichta, Joachim Johansen, Shaina W Twardus, Toni M Delorey, Helena Lau, Hera Vlamakis, James J Moon, Ramnik J Xavier, Daniel B Graham
Journal: Immunity
PubMed ID: 36115338
Doi: 10.1016/j.immuni.2022.08.016
Products & Services: Proteins, Expression, Isolation and Analysis   
Vaspin Ameliorates Cardiac Remodeling by Suppressing Phosphoinositide 3-Kinase/Protein Kinase B Pathway to Improve Oxidative Stress in Heart Failure Rats
Authors: Mingyue Ji, Yong Li, Yun Liu, Genshan Ma
Journal: J Cardiovasc Pharmacol
PubMed ID: 36067399
Doi: 10.1097/FJC.0000000000001291
Products & Services: Custom DNA/RNA Oligos   
Disruption of grin2B, an ASD-associated gene, produces social deficits in zebrafish
Authors: Josiah D Zoodsma, Emma J Keegan, Gabrielle R Moody, Ashwin A Bhandiwad, Amalia J Napoli, Harold A Burgess, Lonnie P Wollmuth, Howard I Sirotkin
Journal: Mol Autism
PubMed ID: 36138431
Doi: 10.1186/s13229-022-00516-3
Products & Services: Gene Synthesis   
Overexpression of NDST1 Attenuates Fibrotic Response in Murine Adipose-Derived Stem Cells
Authors: Takayoshi Otsuka, Ho-Man Kan, Timothy D Mason, Lakshmi S Nair, Cato T Laurencin
Journal: Stem Cells Dev
PubMed ID: 35920108
Doi: 10.1089/scd.2022.0053
Products & Services: Plasmid DNA Preparation   
Nanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals
Authors: Ayumu Inutsuka, Sho Maejima, Hiroyuki Mizoguchi, Ryosuke Kaneko, Rei Nomura, Keiko Takanami, Hirotaka Sakamoto, Tatsushi Onaka
Journal: Commun Biol
PubMed ID: 36114373
Doi: 10.1038/s42003-022-03944-2
Products & Services: Codon Optimization