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Modulation of sphingosine-1-phosphate and apolipoprotein M levels in the plasma， liver and kidneys in streptozotocin-induced diabetic mice.

J Diabetes Investig. 2014; 
Nojiri Takahiro，Kurano Makoto，Tokuhara Yasunori，Ohkubo Shigeo，Hara Masumi，Ikeda Hitoshi，Tsukamoto Kazuhisa，Yatomi Yu
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Catalog Antibody ApoM antibody (GenScript Co, Piskataway, NJ, USA), anti- human ApoM serum (developed in a previously reported paper12) and anti-b-actin antibody (MBL, Nagoya, Japan). Get A Quote

摘要

Sphingosine-1-phosphate (S1P)， a multifunctional bioactive lipid mediator， is involved in various diseases. Apolipoprotein M (ApoM) carries S1P on high-density lipoprotein and modulates S1P metabolism to increase the total S1P mass in the body. Both S1P and ApoM are involved in diabetes.

关键词

Apolipoprotein M，Sphingosine-1-phosphate，Streptozotocin-induced diabetes
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