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Prime-boost vaccination with recombinant protein and adenovirus-vector expressing Plasmodium vivax circumsporozoite protein (CSP) partially protects mice against Pb/Pv sporozoite challenge.
Scientific REPORTS.2018-01;
Tarsila Mendes de Camargo, Elisângela Oliveira de Freitas, Alba Marina Gimenez, Luciana Chagas Lima, Karina de Almeida Caramico, Kátia Sanches Françoso, Oscar Bruna-Romero, Chiara Andolina, François Nosten, Laurent Rénia, Hildegund C. J. Ertl, Ruth S. Nussenzweig, Victor Nussenzweig, Mauricio M. Rodrigues, Arturo Reyes-Sandoval & Irene S. Soares
. As for yPvCSP-AllFL, a synthetic gene codon-optimised for expression in P. pastoris yeast was obtained commercially (GenScript USA Inc., Piscataway, NJ).
