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Human β-defensin 2 plays a regulatory role in innate antiviral immunity and is capable of potentiating the induction of antigen-specific immunity.

Virol. J.. 2018-01; 
KimJu,YangYe Lin,JangSun-Hee,JangYong
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Gene Synthesis … with minor modifications [11]. Briefly, the gene encoding S RBD was synthesized with codon optimization based on the MERS-CoV S protein sequence (GenBank: AKL59401.1; GenScript, Piscataway, NJ, USA). The S RBD … Get A Quote

摘要

Antimicrobial peptides (AMPs) are primarily known for their innate immune defense against invading microorganisms, including viruses. In addition, recent research has suggested their modulatory activity in immune induction. Given that most subunit vaccines require an adjuvant to achieve effective immune induction through the activation of innate immunity, AMPs are plausible candidate molecules for stimulating not only innate immune but also adaptive immune responses.

关键词

Adjuvant,Antibody,Antigen,Human β-defensin,MERS