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Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction.

Int. J. Cardiol.. 2018-01; 
QinQing，DelrioSilvia，WanJunxiang，Jay WidmerR，CohenPinchas，LermanLilach O，Lerman
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Gene Synthesis … The aortic rings from rats were precontracted with 10 − 6 mol/l phenylephrine, and then relaxant responses to MOTS-c (Genscript, USA) were recorded by adding cumulative doses of MOTS-c (0.1 ng/ml to 1 μg/ml) to the tissue bath at 5 min intervals … Get A Quote

摘要

MOTS-c is one of the newly identified mitochondrial-derived peptides which play a role in regulating metabolic homeostasis. The current study aimed to investigate whether circulating MOTS-c levels are also associated with endothelial dysfunction(ED) in patients without significant structural coronary lesions.

关键词

Endothelial dysfunction，MOTS-c，Mitochondrial derived pep
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