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In situ administration of cytokine combinations induces tumor regression in mice.

EBioMedicine. 2018-10; 
ZhangJinyu，JiangHaochen，ZhangHa
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Gene Synthesis … The DNA sequence encoding a reverse tet transactivator protein (rtTA) was synthesized (Genscript) and subcloned into the lentiviral vector pLentis-CMV-MCS-IRES-Bsd between the BamHI and XhoI sites, generating the lentiviral vector pLentis-CMV-rtTA-IRES-Bsd … Get A Quote

摘要

Recent advances in cancer immunotherapy suggest a possibility of harnessing the immune system to defeat malignant tumors， but the complex immunosuppressive microenvironment confines the therapeutic benefits to a minority of patients with solid tumors.

关键词

Cytokine combinations，Immunotherapy，Synergistic antitumor effect，T
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