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Rescue and characterization of recombinant cedar virus, a non-pathogenic Henipavirus species.

Virol. J.. 2018-01; 
LaingEric D,AmayaMoushimi,NavaratnarajahChanakha K,FengYan-Ru,CattaneoRoberto,WangLin-Fa,BroderChristoph
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Gene Synthesis … guidelines. To construct the rCedPV antigenome clone, large DNA fragments of CedPV based on the Cedar virus isolate CG1a sequence, NCBI Accession number NC_025351.1 were synthesized (GenScript; NJ, USA). These … Get A Quote

摘要

Hendra virus and Nipah virus are zoonotic viruses that have caused severe to fatal disease in livestock and human populations. The isolation of Cedar virus, a non-pathogenic virus species in the genus Henipavirus, closely-related to the highly pathogenic Hendra virus and Nipah virus offers an opportunity to investigate differences in pathogenesis and receptor tropism among these viruses.

关键词

Cedar virus,Ephrin ligands,Henipaviruses,Paramyxoviridae,Receptor tropism,Recombinant virus,Reverse gene