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Identification of paeoniflorin from Paeonia lactiflora pall As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice
Authors: Xiaoxia Liang, Ting Su, Pingzhou Wu, Yanting Dai, Yanmin Chen, QiQi Wang, Cheng Cao, Fenglian Chen, Qing Wang, Shuling Wang
Journal: J Ethnopharmacol
PubMed ID: 37315645
Doi: 10.1016/j.jep.2023.116714
Products & Services: Proteins, Expression, Isolation and Analysis   
Antibody aggregation can lead to reduced Protein A binding capacity and low step yield
Authors: Gaoya Yuan, Meng Qu, Qi Geng, Wanyuan Dong, Xudong Zhang, Yifeng Li
Journal: Protein Expr Purif
PubMed ID: 37271409
Doi: 10.1016/j.pep.2023.106315
Products & Services: Proteins, Expression, Isolation and Analysis   
Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models
Authors: Sujin Zhou, Yan Lin, Zhenggang Zhao, Yunhao Lai, Mengmeng Lu, Zishen Shao, Xinyu Mo, Yunping Mu, Zhipeng Liang, Xinxing Wang, Jingming Qu, Hua Shen, Fanghong Li, Allan Z Zhao
Journal: Cell Rep Med
PubMed ID: 37269826
Doi: 10.1016/j.xcrm.2023.101070
Products & Services: Custom Vector Construction   
Effect of moderate prenatal ethanol exposure on the differential expression of two histamine H3 receptor isoforms in different brain regions of adult rat offspring
Authors: Suzy Davies, Kiana S Lujan, Ella J Rappaport, Carlos F Valenzuela, Daniel D Savage
Journal: Front Neurosci
PubMed ID: 37449267
Doi: 10.3389/fnins.2023.1192096
Products & Services: Proteins, Expression, Isolation and Analysis   
Multisite transformation in : insights on transformations mechanisms and new genetic modification protocols
Authors: Vui Yin Seow, Olga Tsygelnytska, Nicolas Biais
Journal: Front Microbiol
PubMed ID: 37408636
Doi: 10.3389/fmicb.2023.1178128
Products & Services: Gene Synthesis   
MERS-CoV RBD-mRNA vaccine induces potent and broadly neutralizing antibodies with protection against MERS-CoV infection
Authors: Wanbo Tai, Jian Zheng, Xiujuan Zhang, Juan Shi, Gang Wang, Xiaoqing Guan, Jiang Zhu, Stanley Perlman, Lanying Du
Journal: Virus Res
PubMed ID: 37336390
Doi: 10.1016/j.virusres.2023.199156
Products & Services: Molecular Biology Reagents   
Two Recombinant Bacteriocins, Rhamnosin and Lysostaphin, Show Synergistic Anticancer Activity Against Gemcitabine-Resistant Cholangiocarcinoma Cell Lines
Authors: Kankamol Kerdkumthong, Wannarat Chanket, Phanthipha Runsaeng, Sutthipong Nanarong, Kawinnath Songsurin, Phonprapavee Tantimetta, Chanan Angsuthanasombat, Aratee Aroonkesorn, Sumalee Obchoei
Journal: Probiotics Antimicrob Proteins
PubMed ID: 37294416
Doi: 10.1007/s12602-023-10096-0
Products & Services: Molecular Biology Reagents   
GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults
Authors: Christine D Palmer, Ciaran D Scallan, Lauren D Kraemer Tardif, Melissa A Kachura, Amy R Rappaport, Daniel O Koralek, Alison Uriel, Leonid Gitlin, Joshua Klein, Matthew J Davis, Harshni Venkatraman, Meghan G Hart, Jason R Jaroslavsky, Sonia Kounlavouth, Martina Marrali, Charmaine N Nganje, Kyounghwa Bae, Tiffany Yan, Katharyn Leodones, Milana Egorova, Sue-Jean Hong, Jenchun Kuan, Silvia Grappi, Pedro Garbes, Karin Jooss, Andrew Ustianowski
Journal: Nat Commun
PubMed ID: 37280238
Doi: 10.1038/s41467-023-39053-9
Products & Services: Peptide Synthesis   
Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS
Authors: Yuta Adachi, Ryo Kimura, Kentaro Hirade, Shogo Yanase, Yuki Nishioka, Natsumi Kasuga, Rui Yamaguchi, Hiromichi Ebi
Journal: Nat Cancer
PubMed ID: 37277529
Doi: 10.1038/s43018-023-00575-2
Products & Services: PCR Cloning and Subcloning   
Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters
Authors: Changxu Pang, Jin Chai, Ping Zhu, John Shanklin, Qun Liu
Journal: Nat Commun
PubMed ID: 37296139
Doi: 10.1038/s41467-023-39010-6
Products & Services: Gene Synthesis   
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