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页码: 44/364 每页显示数量
Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia
Authors: Wenhua Jiang, Qiangqiang Hou, Hongrui Xu, Kexin Yang, Xiaohui Wang, Kuojun Zhang, Yi Zeng, Wenqiang Li, Bingrui Wang, Guangmei Luo, Xiaofan Zhao, Hui Shen, Yong Xu, Xiaoxing Wu
Journal: J Med Chem
PubMed ID: 38175809
Doi: 10.1021/acs.jmedchem.3c02104
Inter-alpha-trypsin inhibitor (IαI) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung
Authors: Fengying Tang, Stephen R Reeves, Jourdan E Brune, Mary Y Chang, Christina K Chan, Peter Waldron, Sheona P Drummond, Caroline M Milner, Kimberly M Alonge, Stavros Garantziotis, Anthony J Day, William A Altemeier, Charles W Frevert
Journal: Matrix Biol
PubMed ID: 38232913
Doi: 10.1016/j.matbio.2024.01.004
KDM6A Demethylase Regulates Renal Sodium Excretion and Blood Pressure
Authors: Xiaobin Han, Leah Akinseye, Zhongjie Sun
Journal: Hypertension
PubMed ID: 38164755
Doi: 10.1161/HYPERTENSIONAHA.123.22026
Efficient treatment of colon cancer with codelivery of TRAIL and imatinib by liposomes
Authors: Rongrong Fu, Rui Chang, Andong Peng, Changshun Feng, Weifan Zhu, Yi Chen, Xue Tian, Rui Wang, Hui Yan, Dianlong Jia, Jun Li
Journal: Pharm Dev Technol
PubMed ID: 38230653
Doi: 10.1080/10837450.2024.2301763
Host protein EPCAM interacting with EtMIC8-EGF is essential for attachment and invasion of Eimeria tenella in chickens
Authors: Lingyu Sun, Chao Li, Ningning Zhao, Bingxiang Wang, Hongmei Li, Hairong Wang, Xiao Zhang, Xiaomin Zhao
Journal: Microb Pathog
PubMed ID: 38281605
Doi: 10.1016/j.micpath.2024.106549
Mitochondrial Homeostasis Regulating Mitochondrial Number and Morphology Is a Distinguishing Feature of Skeletal Muscle Fiber Types in Marine Teleosts
Authors: Busu Li, Huan Wang, Xianghui Zeng, Shufang Liu, Zhimeng Zhuang
Journal: Int J Mol Sci
PubMed ID: 38338790
Doi: 10.3390/ijms25031512
Capsid protein mediated evasion of IRAK1-dependent signalling is essential to Sindbis virus neuroinvasion and virulence in mice
Authors: V Douglas Landers, Milton Thomas, Cierra M Isom, Deepa Karki, Kevin J Sokoloski
Journal: Emerg Microbes Infect
PubMed ID: 38164715
Doi: 10.1080/22221751.2023.2300452
A metalloprotein nanoparticle scaffold co-delivers antigens and adjuvants with metal-enhanced STING activation for vaccination preventing viral infections
Authors: Jiexin Li , Qian Qiu , He Ren , Jingyu Zhang , Chen Zhang , Gengqi Liu , Boyang Sun , Bin Zheng , Jonathan F. Lovell , Yumiao Zhang
Journal: Nano Today
Doi: 10.1016/j.nantod.2024.102156
Remodelling the inguinal adipose sensory system to switch on the furnace: Electroacupuncture stimulation induces brown adipose thermogenesis
Authors: Mengjiang Lu , Ziwei Yu , Xingyu Yang , Li An , Xinyue Jing , Tiancheng Xu , Mengqian Yuan , Bin Xu , Zhi Yu
Journal: Diabetes Obes Metab .
PubMed ID: 38229447
Doi: 10.1111/dom.15444
Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity
Authors: Ying Meng, Iredia D Iyamu, Noha A M Ahmed, Rong Huang
Journal: ACS Chem Biol
PubMed ID: 38181447
Doi: 10.1021/acschembio.3c00531
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