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Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors

Authors: Zhang Z, Jing J, Ye Y, Chen Z, Jing Y, Li S, Hong W, Ruan H, Liu Y, Hu Q, Wang J, Li W, Lin C, Diao L, Zhou Y, Han L

Journal: Genome medicine

PubMed ID: 33225964

Doi: 10.1186/s13073-020-00795-6

Products & Services: Proteins, Expression, Isolation and Analysis

On the shuttling across the blood-brain barrier via tubule formation: Mechanism and cargo avidity bias.

Authors: Tian X,Leite DM,Scarpa E,Nyberg S,Fullstone G,Forth J,Matias D,Apriceno A,Poma A,Duro-Castano A,Vuyyuru M,Harker-Kirschneck L,Šarić A,Zhang Z,Xiang P,Fang B,Tian Y,Luo L,Rizzello L,Battaglia G

Journal: SCIENCE ADVANCES

PubMed ID: 33246953

Doi: 10.1126/sciadv.abc4397

Products & Services: Recombinant Proteins

Short-duration splice promoting compound enables a tunable mouse model of spinal muscular atrophy

Authors: Anne Rietz, Kevin J Hodgetts, Hrvoje Lusic, Kevin M Quist, Erkan Y Osman, Christian L Lorson, Elliot J Androphy

Journal: Life Sci Alliance

PubMed ID: 33234679

Doi: 10.26508/lsa.202000889

Products & Services: Proteins, Expression, Isolation and Analysis

The 3 2-Å resolution structure of human mTORC2

Authors: Scaiola A,Mangia F,Imseng S,Boehringer D,Berneiser K,Shimobayashi M,Stuttfeld E,Hall MN,Ban N,Maier T