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Engineering, structure, and immunogenicity of a Crimean-Congo hemorrhagic fever virus pre-fusion heterotrimeric glycoprotein complex

Authors: Elizabeth McFadden, Stephanie R Monticelli, Albert Wang, Ajit R Ramamohan, Thomas G Batchelor, Ana I Kuehne, Russell R Bakken, Alexandra L Tse, Kartik Chandran, Andrew S Herbert, Jason S McLellan

Journal: biorxiv

PubMed ID: 38659837

Doi: 10.1101/2024.04.20.590419

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Decoding chromatin states by proteomic profiling of nucleosome readers

Authors: Saulius Lukauskas, Andrey Tvardovskiy, Nhuong V Nguyen , Mara Stadler, Peter Faull, Tina Ravnsborg, Bihter Özdemir Aygenli, Scarlett Dornauer, Helen Flynn, Rik G H Lindeboom, Teresa K Barth, Kevin Brockers, Stefanie M Hauck, Michiel Vermeulen, Ambrosius P Snijders, Christian L Müller, Peter A DiMaggio, Ole N Jensen, Robert Schneider, Till Bartke

Journal: Nature

PubMed ID: 38448585

Doi: 10.1038/s41586-024-07141-5

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Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models

Authors: Franziska K Kaiser, Mariana Gonzalez Hernandez, Nadine Krüger, Ellinor Englund, Wenjuan Du, Anna Z Mykytyn, Mathijs P Raadsen, Mart M Lamers

Journal: Nature Communications

PubMed ID: 38485931

Doi: 10.1038/s41467-024-46443-0

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An alphacoronavirus polymerase structure reveals conserved replication factor functions

Authors: Thomas K Anderson, Peter J Hoferle, Kennan J Chojnacki, Kenneth W Lee, Joshua J Coon, Robert N Kirchdoerfer

Journal: Nucleic Acids Research

PubMed ID: 38442273

Doi: 10.1093/nar/gkae153

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Highly stable and immunogenic CMV T cell vaccine candidate developed using a synthetic MVA platform

Authors: Marcal Yll-Pico, Yoonsuh Park, Joy Martinez, Angelina Iniguez, Mindy Kha, Taehyun Kim, Leonard Medrano, Vu H Nguyen, Teodora Kaltcheva, Shannon Dempsey, Flavia Chiuppesi, Felix Wussow, Don J Diamond

Journal: npj Vaccines

PubMed ID: 38555379

Doi: 10.1038/s41541-024-00859-3

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EGFR amplification and EGFRvIII predict and participate in TAT-Cx43266-283 antitumor response in preclinical glioblastoma models

Authors: Andrea Álvarez-Vázquez, Laura San-Segundo, Pilar Cerveró-García, Raquel Flores-Hernández, Claudia Ollauri-Ibáñez, Berta Segura-Collar, C G Hubert, Gillian Morrison, Steven M Pollard, Justin D Lathia, Pilar Sánchez-Gómez, Arantxa Tabernero

Journal: Neuro Oncol

PubMed ID: 38507464

Doi: 10.1093/neuonc/noae060

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Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity

Authors: Lucy Rutten, Maarten Swart, Annemart Koornneef, Pascale Bouchier, Sven Blokland, Ava Sadi, Jarek Juraszek, Aneesh Vijayan, Sonja Schmit-Tillemans, Johan Verspuij, Ying Choi, Chenandly E Daal, Aditya Perkasa, Shessy Torres Morales, Sebenzile K Myeni, Marjolein Kikkert, Jeroen Tolboom, Daniëlle van Manen, Harmjan Kuipers, Hanneke Schuitemaker, Roland Zahn, Johannes P M Langedijk

Journal: Sci Rep

PubMed ID: 38459086

Doi: 10.1038/s41598-024-56293-x

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MiR-326 sponges TET2 triggering imbalance of Th17/Treg differentiation to exacerbate pyroptosis of hepatocytes in concanavalin A-induced autoimmune hepatitis

Authors: Genglin Zhang, Sensen Wu, Guangtao Xia

Journal: Hepatology

PubMed ID: 38043702

Doi: 10.1016/j.aohep.2023.101183

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Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division

Authors: Phillip Nußbaum, Danguole Kureisaite-Ciziene, Dom Bellini, Chris van der Does, Marko Kojic, Najwa Taib, Anna Yeates, Maxime Tourte, Simonetta Gribaldo, Martin Loose, Jan Löwe, Sonja-Verena Albers

Journal: Nat Microbiol

PubMed ID: 38443575

Doi: 10.1038/s41564-024-01600-5

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An Engineered Laccase from Accelerates Lignocellulose Degradation

Authors: Le Thanh Mai Pham, Kai Deng, Hemant Choudhary, Trent R Northen, Steven W Singer, Paul D Adams, Blake A Simmons, Kenneth L Sale

Journal: Biomolecules

PubMed ID: 38540744

Doi: 10.3390/biom14030324

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