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目录产品 » VCAM-1/CD106, His, Mouse
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VCAM-1/CD106, His, Mouse

Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages and T cells.
￥3500
Z06400-100

产品简介
Species Mouse
Protein Construction
VCAM-1/CD106 (Phe25-Glu698)_x000D_
Accession # NP_035823.3		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by the ability of the immobilized protein to support adhesion of U937 human histiocytic lymphoma cells. Test result meets the standard.
Expression System HEK293
Theoretical Molecular Weight 75.48 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
VCAM-1/CD106, His, Mouse

The purity of VCAM-1/CD106, His, Mouse is greater than 95% as determined by SEC-HPLC. »

VCAM-1/CD106, His, Mouse

VCAM-1/CD106, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associated vascular adhesion and the transendothelial migration of leukocytes, such as macrophages and T cells.
Synonyms V-CAM 1; VCAM-1; INCAM-100; CD106; DKFZp779G2333; MGC99561
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.