| ￥3300 | |
| Z05873-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 44.2 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 50-68 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized Human Mature TGF beta 1, No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for TGF-beta RII/TGFBR2 hFc Chimera, Human, hFc Tag with the EC50 of 11.0ng/ml determined by ELISA. »
The purity of TGF-beta RII/TGFBR2 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »
TGF-beta RII/TGFBR2 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
TGF-beta RII/TGFBR2 hFc Chimera, Human, hFc Tag captured on CM5 Chip via Protein A can bind Human Latent TGF beta 2, His Tag with an affinity constant of 2.21 μM as determined in SPR assay (Biacore T200). »
| Target Background | The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. |
| Synonyms | TGFR2; TGFBR2; TbetaR-II; TGFβR2; TbetaR-II; TGFβR2; AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TβR-II; TβR-II |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
