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目录产品 » SIRP Gamma/CD172g, His & Avi, Human
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SIRP Gamma/CD172g, His & Avi, Human

Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
￥2500
Z05842-100

产品简介
Species Human
Protein Construction
SIRP Gamma/CD172g (Glu29-Pro360)_x000D_
Accession # Q9P1W8		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 39.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 45-52 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
SIRP Gamma/CD172g, His & Avi, Human

Immobilized SIRP Gamma/CD172g, His & Avi, Human, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human CD47, hFc Tag with the EC50 of 2.25μg/ml determined by ELISA. »

SIRP Gamma/CD172g, His & Avi, Human

The purity of SIRP Gamma/CD172g, His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

SIRP Gamma/CD172g, His & Avi, Human

SIRP Gamma/CD172g, His & Avi, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. »

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技术背景
Target Background Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Synonyms CD172g; FLJ42230; SIRP beta 2; SIRP gamma; SIRP-B2; SIRPG; Cripto-1; bA77C3.1; SIRP β 2; SIRPγ; SIRP γ
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.