| ￥2500 | |
| Z05727-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by Bis-Tris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 46.8 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 70-78 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Loaded OX40/TNFRSF4/CD134 hFc Chimera, Human, hFc Tag on ProA-Biosensor, can bind Human OX40 Ligand (Trimer), His Tag with an affinity constant of 0.16 nM as determined in BLI assay (Gator® Prime). »
Immobilized Human OX40 Ligand (Trimer), His Tag at 1 μg/ml(100 μl/well) on the plate. Dose response curve for OX40/TNFRSF4/CD134 hFc Chimera, Human, hFc Tag with the EC50 of 34.2ng/ml determined by ELISA. »
The purity of OX40/TNFRSF4/CD134 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »
OX40/TNFRSF4/CD134 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |
| Synonyms | CD134; OX40; OX40L receptor; TNFRSF4; ACT-135; Ly-70; OX40 homologue; TXGP1L; IMD16 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
