| ￥4100 | |
| Z05530-100 | |
|
|
|
|
|
|
|
|
|
| Species | Human | ||||||
| Protein Construction |
|
||||||
| Purity | > 95% as determined by BisTris PAGE | ||||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||||
| Expression System | HEK293 | ||||||
| Theoretical Molecular Weight | 114 kDa (ITGAV) & 81.3 kDa (ITGB3) | ||||||
| Apparent Molecular Weight | Due to glycosylation,the protein migrates to 85-140 kDa based on Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer, His & Avi, Human, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA. »
The purity of Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer, His & Avi, Human is greater than 95% as determined by SEC-HPLC. »
Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer, His & Avi, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. »
| Target Background | ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling. |
| Synonyms | αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3;Integrin alpha V β 3; β3 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
