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目录产品 » Complement C2, His, Cynomolgus

Complement C2, His, Cynomolgus

Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC.
¥3500
Z04768-100

Species Cynomolgus
Protein Construction
Complement C2 (Ala21-Leu752)
Accession # XP_005553508.1
His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its ability to cleave a colorimetric peptide substrate, N­carbobenzyloxy­Gly­ArgThioBenzyl ester (Z­GR­SBzl), in the presence of 5,5'Dithio­bis (2­nitrobenzoic acid) (DTNB). Test result meets the standard.
Expression System HEK293
Theoretical Molecular Weight 82.18 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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Complement C2, His, Cynomolgus

The purity of Complement C2, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »

Complement C2, His, Cynomolgus

Complement C2, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Target Background Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC.
Synonyms Complement Component C2; C3/C5 convertase; C2; ARMD14; CO2
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.