ACE-2 Fc Chimera, Human
ACE-2 Fc Chimera, Human (CHO-expressed)
| 询价 | |
| T80801-0.1 | |
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| 询价 | |
| T80801-0.1 | |
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| Species | Human |
| Tag | Fc tag |
| Purity | ≥ 95% as analyzed by SDS-PAGE |
| Biological Activity | ACE-2 Fc Chimera, Human (CHO-expressed) can bind with S-RBD in functional ELISA assay |
| Source | CHO |
| Molecular Weight | 110.5 KD (predicted on protein sequence) |
| Formulation | Liquid, PBS, pH 7.4 |
| Storage buffer | PBS pH 7.4 |
| Storage | The product remains stable for 6 months at -20° C or below from date of receipt. Avoid repeated freeze-thaw cycles. |
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| Synonyms | Human Angiotensin-Converting Enzyme 2, ACE-2 |
| Target Background |
Angiotensin-Converting Enzyme 2 (ACE-2) is an
integral membrane protein and a zinc
metalloprotease of the ACE family. The ACE
family includes somatic and germinal ACE.
ACE-2 cleaves angiotensins I and II as a
carboxypeptidase. ACE-2 converts angiotensin I
to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze
apelin-13 and dynorphin-13 with high efficiency.
ACE-2 Fc Chimera, Human (CHO-expressed)
carries a human IgG1 Fc tag at the C-terminus.
It has high binding affinity to S-RBD. ACE-2 Fc Chimera, Human (CHO-expressed) (Z03516) has higher SEC purity and better batch-to-batch stability than ACE-2 Fc Chimera, Human (Z03484). |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
